Medicare Part D Opioid Prescribing Integrity Analytics

Peer normalized analytical framework identifying high risk prescribing patterns through machine learning and statistical validation

Medicare Part D Payments
$128.2B
Annual payments to plans
Excess Costs Quantified
$1.22B
95% CI: $1.21 to $1.24 billion
High Risk Prescribers
51,660
5.0% of 1.03M analyzed
Part D Improper Payments
$3.58B
3.70% annual rate (CMS data)
Method Concordance
61.6%
ML and statistical agreement
Peer Groups Created
2,020
196 specialties × 61 jurisdictions

Top 5 States by Excess Medicare Costs

Validation Performance Metrics

Risk Score Distribution

Geographic Anomaly Rates

System Performance Metrics

Metric Value Significance
Total Prescribers Analyzed 1.38 million Complete Medicare Part D population
Final Analysis Set 1,033,188 74.8% retention after filtering
Processing Time 47.3 seconds Real time analysis capability
Peer Groups Established 2,020 Specialty state combinations
Medical Specialties 196 Complete specialty coverage
U.S. Jurisdictions 61 All states and territories
Clinical Exclusions 7,701 Oncology and palliative care excluded
Random Seed 42 Fixed for reproducibility

Validation Results

Validation Method Result Interpretation
Method Concordance 61.6% ML and statistical methods reach similar conclusions
Bootstrap Stability 2.3% std error 100 iterations, high statistical confidence
Subsample Correlation 98.7% Random 10% samples produce consistent findings
CMS Audit Alignment 72% Consistency with prior manual Medicare reviews
Temporal Persistence 63% (projected) High risk patterns expected to persist across years

Geographic Distribution (Top 5 States)

State Prescribers Anomalies Rate Excess Cost
Florida 52,847 2,470 4.67% $101.8M
California 89,234 4,327 4.85% $80.2M
Texas 45,623 2,208 4.84% $69.7M
North Carolina 28,456 2,063 7.25% $56.3M
Georgia 22,789 1,102 4.83% $49.5M
Important Note: This system identifies statistical anomalies warranting further investigation, not confirmed fraud or abuse. As the Centers for Medicare & Medicaid Services notes, not all improper payments represent fraud or abuse. Actual recoverable amounts depend on subsequent investigation and enforcement capacity.